Aging, weight fluctuations, and genetics all contribute to fat loss in the face and body, leading to hollowed features, skin laxity, and loss of contour. In the past, restoring volume required either dermal fillers or fat grafting, but Renuva has changed the game.

What Is Renuva?

Renuva is an injectable fat matrix designed to stimulate the body’s natural fat regeneration in areas where volume has been lost. It contains adipose-derived extracellular matrix (ECM), which provides the necessary biochemical cues for your body to rebuild its own fat over time. Said differently, Renuva can be likened to a “trellis” for fat growth. It uses an injectable fat matrix derived from donor fat tissue (with all of the fat cells removed leaving behind the “trellis”), which acts as scaffolding. This matrix integrates with the body and stimulates the natural production of new fat cells in the treated area, gradually replacing the injected material with the body’s own fat over time
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Unlike traditional dermal fillers that simply add volume, Renuva triggers your body to generate its own living fat cells for long-term, natural-looking results.
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"Renuva is essentially a fat graft without the surgery. It uses a biocompatible fat matrix to signal the body to repopulate the area with its own fat cells. This makes it a powerful tool for restoring lost volume in a way that looks and feels completely natural." — Dr. Saami Khalifian

How Renuva Is Used 

At SOM Aesthetics, Dr. Saami uses Renuva as a versatile treatment for volume loss, contour irregularities, and skin texture improvements. Recent data suggests that in addition to growing new fat cells it also improves skin quality. It’s injected strategically into areas where natural fat has diminished, allowing the body to gradually restore lost structure and improve tissue and skin quality over time.

Treatment Process:

Consultation: Every Renuva treatment starts with a customized evaluation to determine the best injection sites based on a patient’s goals.
Injection Session: Renuva is injected into targeted areas using a blunt metal tube called a cannula or a needle. The procedure is quick, minimally invasive, and requires little downtime.
Gradual Volume Restoration: Over the following 3-6 months, the body replaces the Renuva matrix with its own fat cells, leading to long-lasting, natural results.

"I love using Renuva for patients who want long-term, natural volume replacement but aren’t ready for fat grafting. The ability to regenerate your own fat over time is what makes this product stand apart from fillers." — Dr. Saami Khalifian

Who Is the Right Patient for Renuva?

Renuva is ideal for patients who experience volume loss in the face or body but want a natural, long-term solution that doesn’t require surgery.
Best candidates include:
Patients with age-related fat loss who want to restore youthful contours.
Individuals with contour irregularities from previous procedures or trauma.
Those seeking gradual, natural volume replacement instead of synthetic fillers.
Patients who aren’t ready for fat grafting but want a regenerative approach. 

"If you’re noticing hollowing in your face or body but don’t want the upkeep of traditional fillers, Renuva offers a way to rebuild natural volume over time. It’s a regenerative solution, not just a temporary fix." — Dr. Saami Khalifian

What Areas or Problems Can Be Treated With Renuva?

Renuva is extremely versatile, making it an excellent option for a variety of cosmetic concerns.

Common treatment areas include:

Face: Restores volume in the cheeks, temples, jawline, and nasolabial folds. It also improves skin quality, skin radiance, and skin glow. 
Hands: Replenishes lost fat for smoother, more youthful hands.
Buttocks & Hip Dips: A great non-surgical option for mild volume enhancement.
Post-Liposuction Irregularities: Helps smooth out indentations or asymmetries from previous procedures.
Scars & Depressions: Improves contour and texture in areas where fat loss has caused indentations.

Final Thoughts on Renuva

Renuva is redefining volume restoration by working with your body instead of just adding filler. Unlike hyaluronic acid fillers that require maintenance every year or two, Renuva provides long-term improvement by helping your body regenerate its own fat. Notably Renuva also provides excellent synergy when used together with filler to provide fat restoration while the filler provides structural lift that mimics bone. 

"What excites me most about Renuva is its ability to create truly natural, lasting results. The fact that we can now stimulate your body to replace fat loss without surgery is a game-changer in aesthetics." — Dr. Saami Khalifian

If you're interested in learning more about Renuva and whether it’s the right fit for you, schedule a consultation at SOM Aesthetics to explore the possibilities of regenerative volume restoration.
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